1. About 15 percent of patients with inflammatory bowel disease develop erythema nodosum . 2. Erythema nodosum may occur concurrently with fever, malaise, and joint pain and inflammation.3. Additional evaluation should be performed to determine the underlying cause of erythema nodosum . 4. Occasional cases of erythema nodosum and erythema multiforme have been reported. 5. Immune complications include acute glomerulonephritis, rheumatic fever, and erythema nodosum . 6. The ESR is initially very high, and falls as the nodules of erythema nodosum . 7. The most common lesions are erythema nodosum , plaques, maculopapular eruptions, subcutaneous nodules, and lupus pernio. 8. Additionally, patients may present with erythema nodosum , cutaneous pustular vasculitis, and lesions similar to pyoderma gangrenosum. 9. Erythema nodosum is due to inflammation of the underlying subcutaneous tissue, and is characterized by septal panniculitis.10. In sarcoidosis presenting in the Caucasian population, hilar adenopathy and erythema nodosum are the most common initial symptoms.
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